![]() Coughing can cause sore muscles in the chest wall, upper abdomen or diaphragm. Causes: Most persistent chest pain is from a hacking cough. This includes the area from the lower neck to the bottom of the rib cage. Pain or discomfort in the chest (front or back).Findik have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data. The authors declare that they have no conflict of interests. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Written informed consent was obtained from the patient for publication of this case report and any accompanying images. The complete surgical excision is enough for treatment, and prognosis is better than other chondrosarcomas. In conclusion, the extraskeletal chondrosarcoma in anterior mediastinum is very rare and usually overlooked on chest radiography. Also, factors significantly affecting survival were tumor grade and radicality of resection. reported that the 47 primary sarcomas of the mediastinum and mediastinal chondrosarcoma was seen in only one patient. There is no recurrence during two years after surgery. According to reported one article, the primary chondrosarcomas of anterior mediastinum may have a less aggressive clinical course than previously recognized. The patient did not receive radiotherapy because all the surgical margins were tumor-free. In the present case, mediastinal chondrosarcoma was totally resected. The wide local excision is recommended for treatment. Histopathologic examination shows chondrocyte atypias and neoplastic chondrocytes, as seen in our case. reported that the combination of pSUV on PET imaging and histopathologic tumor grading in chondrosarcoma might be helpful for determining a more accurate diagnosis. Mediastinal chondrosarcomas also shares imaging findings with other skeletal and soft-tissue tumors. Also, the mass lesion was marked compressing on the heart.Ĭhest radiography, thorax CT, and MRI depicts lobulated, well-shaped soft tissue mass, as in our case. Precordial chest pain was main symptom in our case. Local pain is the most frequent presenting symptom of patients with this neoplasm. In the present case, chondrosarcoma was located on anterior mediastinum and extraskeletal.Ĭhondrosarcoma is more frequently found in patients from the fourth to seventh decades, with a male predominance. Primary chondrosarcoma of the anterior mediastinum without any continuity with cartilage-containing organs are extremely rare. It may occur in extraskeletal locations and mainly in the soft tissues of the orbit, the cranial and spinal meningeal coverings, and lower limbs. Photomicrograph of the resected tumor showing (Hematoxylin and Eosin, ×400) increased cellularity, marked atypia, and pleomorphism mitosis.Ĭhondrosarcomas are presumably derived from primitive precartilaginous mesenchymal cells. Thorax computed tomography (CT) and magnetic resonance (MR) imaging demonstrated a large and well-shaped mass in the anterior mediastinum and clearly compression of the heart by the mass (Figure 2). But a masslike opacity was seen on the heart (Figure 1). Chest roentgenogram was initially thought to be normal. Case PresentationĪ 45-year-old, nonsmoker male was admitted to the hospital with precordial chest pain. We present a patient with extraskeletal chondrosarcoma in anterior mediastinum, which was located on the heart. Extraskeletal chondrosarcoma in anterior mediastinum is very rare. Extraskeletal chondrosarcoma usually affects the deep soft tissues of the extremities and the region of head and neck. Bone chondrosarcoma usually affects middle-aged to elderly adults, and the pelvic bones, ribs, shoulder girdle, and long bones are the most common locations. BackgroundĬhondrosarcoma is a malignant mesenchymal tumor arising from cartilage-forming tissues involving the bones (bone chondrosarcoma) or the soft tissues (extraskeletal chondrosarcoma). We aimed to present and discuss the radiologic, clinic, and histopathologic features of unusual presentation of extraskeletal chondrosarcoma in a case. The lesion was totally resected, and extraskeletal mediastinal chondrosarcoma was histopathologically diagnosed. A large and well-shaped mass in the anterior mediastinum was seen radiologically, and there was a clearly compression of the heart by the mass. A 45-year-old male patient was admitted to the hospital with precordial chest pain.
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